Assay
Age
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Immunohistochemistry (whole mount)
11.5 DPC
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Cdh1 cadherin 1 (Synonyms: Ecad, E-cad, E-cadherin, L-CAM, UM, uvomorulin) | |
Results | Reference |
1 | J:279716 Braitsch CM, Azizoglu DB, Htike Y, Barlow HR, Schnell U, Chaney CP, Carroll TJ, Stanger BZ, Cleaver O, LATS1/2 suppress NFkappaB and aberrant EMT initiation to permit pancreatic progenitor differentiation. PLoS Biol. 2019 Jul;17(7):e3000382 |
1 | J:145166 Cervantes S, Yamaguchi TP, Hebrok M, Wnt5a is essential for intestinal elongation in mice. Dev Biol. 2009 Feb 15;326(2):285-94 |
1 | J:202949 Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J, Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18042-51 |
1 | J:193400 Domyan ET, Branchfield K, Gibson DA, Naiche LA, Lewandoski M, Tessier-Lavigne M, Ma L, Sun X, Roundabout receptors are critical for foregut separation from the body wall. Dev Cell. 2013 Jan 14;24(1):52-63 |
1 | J:169134 Domyan ET, Ferretti E, Throckmorton K, Mishina Y, Nicolis SK, Sun X, Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2. Development. 2011 Mar;138(5):971-81 |
1 | J:308828 Gilbert RM, Schappell LE, Gleghorn JP, Defective mesothelium and limited physical space are drivers of dysregulated lung development in a genetic model of congenital diaphragmatic hernia. Development. 2021 May 15;148(10):dev199460 |
1 | J:243207 Haque F, Kaku Y, Fujimura S, Ohmori T, Adelstein RS, Nishinakamura R, Non-muscle myosin II deletion in the developing kidney causes ureter-bladder misconnection and apical extrusion of the nephric duct lineage epithelia. Dev Biol. 2017 Jul 01;427(1):121-130 |
1 | J:240020 Herriges JC, Verheyden JM, Zhang Z, Sui P, Zhang Y, Anderson MJ, Swing DA, Zhang Y, Lewandoski M, Sun X, FGF-Regulated ETV Transcription Factors Control FGF-SHH Feedback Loop in Lung Branching. Dev Cell. 2015 Nov 09;35(3):322-32 |
1 | J:174762 Hornblad A, Eriksson AU, Sock E, Hill RE, Ahlgren U, Impaired spleen formation perturbs morphogenesis of the gastric lobe of the pancreas. PLoS One. 2011;6(6):e21753 |
1 | J:185532 Hoshi M, Batourina E, Mendelsohn C, Jain S, Novel mechanisms of early upper and lower urinary tract patterning regulated by RetY1015 docking tyrosine in mice. Development. 2012 Jul;139(13):2405-15 |
1 | J:293575 Hoshi M, Reginensi A, Joens MS, Fitzpatrick JAJ, McNeill H, Jain S, Reciprocal Spatiotemporally Controlled Apoptosis Regulates Wolffian Duct Cloaca Fusion. J Am Soc Nephrol. 2018 Mar;29(3):775-783 |
1 | J:338900 Huang R, Zhang C, Zheng Y, Zhang W, Huang H, Qiu M, Li J, Li F, ISL1 regulates lung branching morphogenesis via Shh signaling pathway. J Biol Chem. 2023 Jul 11;299(8):105034 |
1 | J:167544 Jurado S, Smyth I, van Denderen B, Tenis N, Hammet A, Hewitt K, Ng JL, McNees CJ, Kozlov SV, Oka H, Kobayashi M, Conlan LA, Cole TJ, Yamamoto K, Taniguchi Y, Takeda S, Lavin MF, Heierhorst J, Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis. PLoS Genet. 2010;6(10):e1001170 |
1 | J:213915 Kadzik RS, Cohen ED, Morley MP, Stewart KM, Lu MM, Morrisey EE, Wnt ligand/Frizzled 2 receptor signaling regulates tube shape and branch-point formation in the lung through control of epithelial cell shape. Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12444-9 |
1* | J:172983 Kobayashi H, Kawakami K, Asashima M, Nishinakamura R, Six1 and Six4 are essential for Gdnf expression in the metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defects. Mech Dev. 2007 Apr;124(4):290-303 |
1 | J:221201 Lahtela J, Pradhan B, Narhi K, Hemmes A, Sarkioja M, Kovanen PE, Brown A, Verschuren EW, The putative tumor suppressor gene EphA3 fails to demonstrate a crucial role in murine lung tumorigenesis or morphogenesis. Dis Model Mech. 2015 Apr;8(4):393-401 |
1 | J:324831 Lewis AE, Kuwahara A, Franzosi J, Bush JO, Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting. Cell Rep. 2022 Mar 15;38(11):110510 |
1 | J:275908 Li H, Jakobson M, Ola R, Gui Y, Kumar A, Sipila P, Sariola H, Kuure S, Andressoo JO, Development of the urogenital system is regulated via the 3'UTR of GDNF. Sci Rep. 2019 Mar 28;9(1):5302 |
1 | J:264403 Li Q, Jiao J, Li H, Wan H, Zheng C, Cai J, Bao S, Histone arginine methylation by Prmt5 is required for lung branching morphogenesis through repression of BMP signaling. J Cell Sci. 2018 Jul 25;131(14):jcs217406 |
1 | J:244106 Lin C, Yao E, Zhang K, Jiang X, Croll S, Thompson-Peer K, Chuang PT, YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis. Elife. 2017 Mar 21;6:e21130 |
1 | J:253802 Matsumaru D, Murashima A, Fukushima J, Senda S, Matsushita S, Nakagata N, Miyajima M, Yamada G, Systematic stereoscopic analyses for cloacal development: The origin of anorectal malformations. Sci Rep. 2015 Sep 10;5:13943 |
1* | J:182765 Mork L, Tang H, Batchvarov I, Capel B, Mouse germ cell clusters form by aggregation as well as clonal divisions. Mech Dev. 2012 Jan-Feb;128(11-12):591-6 |
1 | J:275533 Murakami Y, Naganuma H, Tanigawa S, Fujimori T, Eto M, Nishinakamura R, Reconstitution of the embryonic kidney identifies a donor cell contribution to the renal vasculature upon transplantation. Sci Rep. 2019 Feb 4;9(1):1172 |
1 | J:272609 Nantie LB, Young RE, Paltzer WG, Zhang Y, Johnson RL, Verheyden JM, Sun X, Lats1/2 inactivation reveals Hippo function in alveolar type I cell differentiation during lung transition to air breathing. Development. 2018 Nov 9;145(21):dev163105 |
1 | J:173447 Petersen CI, Jheon AH, Mostowfi P, Charles C, Ching S, Thirumangalathu S, Barlow LA, Klein OD, FGF Signaling Regulates the Number of Posterior Taste Papillae by Controlling Progenitor Field Size. PLoS Genet. 2011 Jun;7(6):e1002098 |
1 | J:224142 Reginensi A, Hoshi M, Boualia SK, Bouchard M, Jain S, McNeill H, Yap and Taz are required for Ret-dependent urinary tract morphogenesis. Development. 2015 Aug 1;142(15):2696-703 |
1 | J:171472 Sand FW, Hornblad A, Johansson JK, Loren C, Edsbagge J, Stahlberg A, Magenheim J, Ilovich O, Mishani E, Dor Y, Ahlgren U, Semb H, Growth-limiting role of endothelial cells in endoderm development. Dev Biol. 2011 Apr 15;352(2):267-77 |
1 | J:292836 Sui P, Li R, Zhang Y, Tan C, Garg A, Verheyden JM, Sun X, E3 ubiquitin ligase MDM2 acts through p53 to control respiratory progenitor cell number and lung size. Development. 2019 Dec 16;146(24):dev179820 |
1 | J:174194 Tang N, Marshall WF, McMahon M, Metzger RJ, Martin GR, Control of mitotic spindle angle by the RAS-regulated ERK1/2 pathway determines lung tube shape. Science. 2011 Jul 15;333(6040):342-5 |
1 | J:224386 Wainwright EN, Wilhelm D, Combes AN, Little MH, Koopman P, ROBO2 restricts the nephrogenic field and regulates Wolffian duct-nephrogenic cord separation. Dev Biol. 2015 Aug 15;404(2):88-102 |
1 | J:317033 Xie C, Abrams SR, Herranz-Perez V, Garcia-Verdugo JM, Reiter JF, Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity. Dev Cell. 2021 Dec 20;56(24):3334-3348.e6 |
1 | J:178649 Yang DH, McKee KK, Chen ZL, Mernaugh G, Strickland S, Zent R, Yurchenco PD, Renal collecting system growth and function depend upon embryonic gamma1 laminin expression. Development. 2011 Oct;138(20):4535-44 |
1 | J:170839 Ye X, Wang Y, Rattner A, Nathans J, Genetic mosaic analysis reveals a major role for frizzled 4 and frizzled 8 in controlling ureteric growth in the developing kidney. Development. 2011 Mar;138(6):1161-72 |
1 | J:312414 Yogosawa S, Ohkido M, Horii T, Okazaki Y, Nakayama J, Yoshida S, Toyokuni S, Hatada I, Morimoto M, Yoshida K, Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient. Commun Biol. 2021 Oct 20;4(1):1204 |
1 | J:332095 Zhang K, Yao E, Chuang E, Chen B, Chuang EY, Chuang PT, mTORC1 signaling facilitates differential stem cell differentiation to shape the developing murine lung and is associated with mitochondrial capacity. Nat Commun. 2022 Nov 25;13(1):7252 |
1 | J:324215 Zhang Y, Yokoyama S, Herriges JC, Zhang Z, Young RE, Verheyden JM, Sun X, E3 ubiquitin ligase RFWD2 controls lung branching through protein-level regulation of ETV transcription factors. Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7557-62 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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